The cees dekker Diaries
The cees dekker Diaries
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Spatial construction facilitates cooperation in the social Problem: empirical evidence from the bacterial Local community
Our group studies bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our major curiosity lies in mobile division, chromatin framework, and spatial Handle.
[Laughs] ‘It was definitely a great risk! At some time, I had been nicely informed that it could go Erroneous Which I could turn into a lot less productive, but I just dismissed that. Curiosity has usually been my strongest driving force. And fortunately all of it worked out.’
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2015, discovery that condensin is often a really versatile protein structure; and to start with detection of DNA knots employing nanopores
Microbiology has only been around for any century, due to the fact we began to review micro-organisms extra critically. I thought nanobiology was an proper phrase, due to the fact all molecular Organic appropriate interactions happen with the nanoscale: a protein is a number of nanometres in dimensions, DNA is two nm thick.’
We form germs into types that deviate from their natural phenotype. Specifically, I'll exhibit our capability to shape live E. coli microbes into novel designs for example rectangles, squares, triangles cees dekker and circles.
Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue
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1). The existing–voltage curves showed major modulations with gate voltage, even at space temperature, which was according to band bending within a ~0.six eV bandgap semiconducting nanotube. These info also confirmed that the conductance may very well be modulated by six orders of magnitude by shifting the gate voltage. The results of this work — a area-temperature transistor comprised of an individual carbon nanotube molecule — were being printed in Character in May possibly 1998.
In 1993 he was appointed as Associate Professor at Delft University of Know-how. In the mid-nineties Dekker and his staff accomplished accomplishment with the invention of the electronic Houses of carbon nanotubes, the main single-molecule transistor and also other nanoscience.
‘That concerns the synthetic mobile, as A part of the Dutch BaSyC initiative. Craig Venter appeared leading-down in Those people days and determined about 5 hundred genes which can be minimally demanded for any operating mobile. We want to seem base-up: how do we transfer from the few molecules to a complete Organic procedure?
Visualization of unstained DNA nanostructures with advanced in-target transmission electron microscopy tactics
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments